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Synthetic UKBB South Asian ASCVD (1M Patients)

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This dataset contains 1 million synthetic patients with ancestry (European and South Asian), demographics, anthropometrics, labs, lifestyle/SES, comorbidities, medications, and time-to-event outcomes for ASCVD, heart failure, and atrial fibrillation. The dataset inspired by the published Circulation study.

All data are artificially generated and contain no identifiable patient records.


Dataset Structure

Demographics

  • id — unique patient identifier
  • ancestry — European or SouthAsian
  • age — years
  • sex_male — binary (1 = male, 0 = female)

Anthropometrics

  • height_cm, weight_kg, bmi
  • waist_cm, hip_cm, whr (waist ÷ hip)
  • waist_height_ratio, body_fat_pct, trunk_fat_pct

Blood Pressure

  • sbp_mmHg, dbp_mmHg
  • hypertension (binary)
  • on_bp_meds (binary)

Lipids

  • ldl_mgdl, hdl_mgdl, tg_mgdl
  • apoA_mgdl, apoB_mgdl, lpa_nmolL
  • on_statin (binary)

Metabolic / Inflammatory

  • glucose_mgdl, hba1c_pct, crp_mgL
  • diabetes (binary)
  • on_dm_meds (binary)

Renal

  • creatinine_mgdl, cystatin_c_mgL, egfr_ckd_epi
  • ckd (binary)

Lifestyle / SES

  • smoking_status (never / former / current)
  • pack_years
  • sedentary (binary)
  • pa_met_h_wk (physical activity in MET-hours/week)
  • diet_score
  • education_level
  • income_bracket
  • townsend (deprivation index)
  • psychosocial_stress
  • pct_life_in_uk

Family / History

  • family_history (binary)

Female-Specific (if sex_male = 0)

  • early_menopause, gest_htn, gest_dm, preeclampsia, iugr

Outcomes

  • time_ascvd_yrs, ascvd_event
  • time_hf_yrs, hf_event
  • time_af_yrs, af_event

(For outcomes: time_* = follow-up time in years (capped at 15), *_event = binary indicator)


Example Usage

import pandas as pd

df = pd.read_parquet("ukb_sa_ascvd_synthetic_1m.parquet")
print(df.shape)   # (1000000, ~70 columns)
print(df.head())

Intended Use

  • Educational & personal learning
  • Benchmarking methods for EMR preprocessing, feature extraction, and survival analysis
  • Synthetic data methodology testing

Not for clinical decision-making.

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