Update README.md
Browse files
README.md
CHANGED
|
@@ -1,199 +1,62 @@
|
|
| 1 |
---
|
| 2 |
library_name: transformers
|
| 3 |
-
tags:
|
|
|
|
|
|
|
|
|
|
|
|
|
| 4 |
---
|
| 5 |
|
| 6 |
-
|
| 7 |
|
| 8 |
-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 9 |
|
|
|
|
| 10 |
|
|
|
|
|
|
|
| 11 |
|
| 12 |
-
|
|
|
|
| 13 |
|
| 14 |
-
|
|
|
|
|
|
|
| 15 |
|
| 16 |
-
|
| 17 |
-
|
| 18 |
-
This is the model card of a 🤗 transformers model that has been pushed on the Hub. This model card has been automatically generated.
|
| 19 |
-
|
| 20 |
-
- **Developed by:** [More Information Needed]
|
| 21 |
-
- **Funded by [optional]:** [More Information Needed]
|
| 22 |
-
- **Shared by [optional]:** [More Information Needed]
|
| 23 |
-
- **Model type:** [More Information Needed]
|
| 24 |
-
- **Language(s) (NLP):** [More Information Needed]
|
| 25 |
-
- **License:** [More Information Needed]
|
| 26 |
-
- **Finetuned from model [optional]:** [More Information Needed]
|
| 27 |
-
|
| 28 |
-
### Model Sources [optional]
|
| 29 |
|
| 30 |
<!-- Provide the basic links for the model. -->
|
| 31 |
|
| 32 |
-
- **Repository:**
|
| 33 |
-
- **Paper
|
| 34 |
-
- **Demo [optional]:** [More Information Needed]
|
| 35 |
-
|
| 36 |
-
## Uses
|
| 37 |
-
|
| 38 |
-
<!-- Address questions around how the model is intended to be used, including the foreseeable users of the model and those affected by the model. -->
|
| 39 |
-
|
| 40 |
-
### Direct Use
|
| 41 |
-
|
| 42 |
-
<!-- This section is for the model use without fine-tuning or plugging into a larger ecosystem/app. -->
|
| 43 |
-
|
| 44 |
-
[More Information Needed]
|
| 45 |
-
|
| 46 |
-
### Downstream Use [optional]
|
| 47 |
-
|
| 48 |
-
<!-- This section is for the model use when fine-tuned for a task, or when plugged into a larger ecosystem/app -->
|
| 49 |
-
|
| 50 |
-
[More Information Needed]
|
| 51 |
-
|
| 52 |
-
### Out-of-Scope Use
|
| 53 |
-
|
| 54 |
-
<!-- This section addresses misuse, malicious use, and uses that the model will not work well for. -->
|
| 55 |
-
|
| 56 |
-
[More Information Needed]
|
| 57 |
-
|
| 58 |
-
## Bias, Risks, and Limitations
|
| 59 |
-
|
| 60 |
-
<!-- This section is meant to convey both technical and sociotechnical limitations. -->
|
| 61 |
-
|
| 62 |
-
[More Information Needed]
|
| 63 |
-
|
| 64 |
-
### Recommendations
|
| 65 |
-
|
| 66 |
-
<!-- This section is meant to convey recommendations with respect to the bias, risk, and technical limitations. -->
|
| 67 |
-
|
| 68 |
-
Users (both direct and downstream) should be made aware of the risks, biases and limitations of the model. More information needed for further recommendations.
|
| 69 |
|
| 70 |
## How to Get Started with the Model
|
| 71 |
|
| 72 |
-
|
| 73 |
-
|
| 74 |
-
|
| 75 |
-
|
| 76 |
-
|
| 77 |
-
|
| 78 |
-
|
| 79 |
-
|
| 80 |
-
|
| 81 |
-
|
| 82 |
-
|
| 83 |
-
|
| 84 |
-
|
| 85 |
-
|
| 86 |
-
|
| 87 |
-
|
| 88 |
-
|
| 89 |
-
|
| 90 |
-
|
| 91 |
-
|
| 92 |
-
|
| 93 |
-
#### Training Hyperparameters
|
| 94 |
-
|
| 95 |
-
- **Training regime:** [More Information Needed] <!--fp32, fp16 mixed precision, bf16 mixed precision, bf16 non-mixed precision, fp16 non-mixed precision, fp8 mixed precision -->
|
| 96 |
-
|
| 97 |
-
#### Speeds, Sizes, Times [optional]
|
| 98 |
-
|
| 99 |
-
<!-- This section provides information about throughput, start/end time, checkpoint size if relevant, etc. -->
|
| 100 |
-
|
| 101 |
-
[More Information Needed]
|
| 102 |
-
|
| 103 |
-
## Evaluation
|
| 104 |
-
|
| 105 |
-
<!-- This section describes the evaluation protocols and provides the results. -->
|
| 106 |
-
|
| 107 |
-
### Testing Data, Factors & Metrics
|
| 108 |
-
|
| 109 |
-
#### Testing Data
|
| 110 |
-
|
| 111 |
-
<!-- This should link to a Dataset Card if possible. -->
|
| 112 |
-
|
| 113 |
-
[More Information Needed]
|
| 114 |
-
|
| 115 |
-
#### Factors
|
| 116 |
-
|
| 117 |
-
<!-- These are the things the evaluation is disaggregating by, e.g., subpopulations or domains. -->
|
| 118 |
-
|
| 119 |
-
[More Information Needed]
|
| 120 |
-
|
| 121 |
-
#### Metrics
|
| 122 |
-
|
| 123 |
-
<!-- These are the evaluation metrics being used, ideally with a description of why. -->
|
| 124 |
-
|
| 125 |
-
[More Information Needed]
|
| 126 |
-
|
| 127 |
-
### Results
|
| 128 |
-
|
| 129 |
-
[More Information Needed]
|
| 130 |
-
|
| 131 |
-
#### Summary
|
| 132 |
-
|
| 133 |
-
|
| 134 |
-
|
| 135 |
-
## Model Examination [optional]
|
| 136 |
-
|
| 137 |
-
<!-- Relevant interpretability work for the model goes here -->
|
| 138 |
-
|
| 139 |
-
[More Information Needed]
|
| 140 |
-
|
| 141 |
-
## Environmental Impact
|
| 142 |
-
|
| 143 |
-
<!-- Total emissions (in grams of CO2eq) and additional considerations, such as electricity usage, go here. Edit the suggested text below accordingly -->
|
| 144 |
-
|
| 145 |
-
Carbon emissions can be estimated using the [Machine Learning Impact calculator](https://mlco2.github.io/impact#compute) presented in [Lacoste et al. (2019)](https://arxiv.org/abs/1910.09700).
|
| 146 |
-
|
| 147 |
-
- **Hardware Type:** [More Information Needed]
|
| 148 |
-
- **Hours used:** [More Information Needed]
|
| 149 |
-
- **Cloud Provider:** [More Information Needed]
|
| 150 |
-
- **Compute Region:** [More Information Needed]
|
| 151 |
-
- **Carbon Emitted:** [More Information Needed]
|
| 152 |
-
|
| 153 |
-
## Technical Specifications [optional]
|
| 154 |
-
|
| 155 |
-
### Model Architecture and Objective
|
| 156 |
-
|
| 157 |
-
[More Information Needed]
|
| 158 |
-
|
| 159 |
-
### Compute Infrastructure
|
| 160 |
-
|
| 161 |
-
[More Information Needed]
|
| 162 |
-
|
| 163 |
-
#### Hardware
|
| 164 |
-
|
| 165 |
-
[More Information Needed]
|
| 166 |
-
|
| 167 |
-
#### Software
|
| 168 |
-
|
| 169 |
-
[More Information Needed]
|
| 170 |
-
|
| 171 |
-
## Citation [optional]
|
| 172 |
-
|
| 173 |
-
<!-- If there is a paper or blog post introducing the model, the APA and Bibtex information for that should go in this section. -->
|
| 174 |
-
|
| 175 |
-
**BibTeX:**
|
| 176 |
-
|
| 177 |
-
[More Information Needed]
|
| 178 |
-
|
| 179 |
-
**APA:**
|
| 180 |
-
|
| 181 |
-
[More Information Needed]
|
| 182 |
-
|
| 183 |
-
## Glossary [optional]
|
| 184 |
-
|
| 185 |
-
<!-- If relevant, include terms and calculations in this section that can help readers understand the model or model card. -->
|
| 186 |
-
|
| 187 |
-
[More Information Needed]
|
| 188 |
-
|
| 189 |
-
## More Information [optional]
|
| 190 |
-
|
| 191 |
-
[More Information Needed]
|
| 192 |
-
|
| 193 |
-
## Model Card Authors [optional]
|
| 194 |
-
|
| 195 |
-
[More Information Needed]
|
| 196 |
-
|
| 197 |
-
## Model Card Contact
|
| 198 |
-
|
| 199 |
-
[More Information Needed]
|
|
|
|
| 1 |
---
|
| 2 |
library_name: transformers
|
| 3 |
+
tags:
|
| 4 |
+
- DNA
|
| 5 |
+
- genomics
|
| 6 |
+
datasets:
|
| 7 |
+
- omicseye/prok_heavy
|
| 8 |
---
|
| 9 |
|
| 10 |
+
## Introduction
|
| 11 |
|
| 12 |
+
The seqLens models are a collection of genomic language models.
|
| 13 |
+
seqLens models leverage an extensive dataset of 19,551 reference genomes,
|
| 14 |
+
including over 18,000 prokaryotic genomes (115B nucleotides),
|
| 15 |
+
alongside a more balanced dataset of 1,354 genomes spanning 1,166 prokaryotic and 188 eukaryotic reference genomes (180B nucleotides).
|
| 16 |
+
Through systematic evaluation of 52 DNA language models with varying architectures, hyperparameters, and classification heads,
|
| 17 |
+
we developed seqLens, a family of models based on disentangled attention with relative positional encoding.
|
| 18 |
+
These models demonstrate superior performance, outperforming state-of-the-art methods in phenotypic predictions.
|
| 19 |
+
The seqLens models provide a robust foundation for optimizing DNA language models and advancing genome annotations across diverse biological contexts.
|
| 20 |
|
| 21 |
+
- **Developed by:** omicseye
|
| 22 |
|
| 23 |
+
- **Model type:** Encoder
|
| 24 |
+
- **Language(s) (NLP):** DNA
|
| 25 |
|
| 26 |
+
- **pretraining dataset:** omicseye/prok_heavy
|
| 27 |
+
- **License:** The model is made available under the [CC-BY-NC 4.0 License]. For inquiries about commercial licensing, please contact [email protected].
|
| 28 |
|
| 29 |
+
<p align="center">
|
| 30 |
+
<img width="100%" src="https://github.com/omicsEye/seqLens/blob/main/visualizations/plots/png/model_performance_all.png?raw=true">
|
| 31 |
+
</p>
|
| 32 |
|
| 33 |
+
### Model Sources
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 34 |
|
| 35 |
<!-- Provide the basic links for the model. -->
|
| 36 |
|
| 37 |
+
- **Repository:** https://github.com/omicsEye/seqLens
|
| 38 |
+
- **Paper:** https://doi.org/10.1101/2025.03.12.642848
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 39 |
|
| 40 |
## How to Get Started with the Model
|
| 41 |
|
| 42 |
+
```python
|
| 43 |
+
from transformers import AutoTokenizer, AutoModelForMaskedLM
|
| 44 |
+
|
| 45 |
+
tokenizer = AutoTokenizer.from_pretrained("omicseye/seqLens_8192_512_30M")
|
| 46 |
+
model = AutoModelForMaskedLM.from_pretrained("omicseye/seqLens_8192_512_30M")
|
| 47 |
+
```
|
| 48 |
+
|
| 49 |
+
## Citation
|
| 50 |
+
```bibtex
|
| 51 |
+
@article {seqLens,
|
| 52 |
+
author = {Baghbanzadeh, Mahdi and Mann, Brendan and Crandall, Keith A and Rahnavard, Ali},
|
| 53 |
+
title = {seqLens: optimizing language models for genomic predictions},
|
| 54 |
+
elocation-id = {2025.03.12.642848},
|
| 55 |
+
year = {2025},
|
| 56 |
+
doi = {10.1101/2025.03.12.642848},
|
| 57 |
+
publisher = {Cold Spring Harbor Laboratory},
|
| 58 |
+
URL = {https://www.biorxiv.org/content/early/2025/03/14/2025.03.12.642848},
|
| 59 |
+
eprint = {https://www.biorxiv.org/content/early/2025/03/14/2025.03.12.642848.full.pdf},
|
| 60 |
+
journal = {bioRxiv}
|
| 61 |
+
}
|
| 62 |
+
```
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|