Provide a detailed explanation of how enzymes function in biochemical reactions, including their role in lowering activation energy and their specificity to substrates. Your response should contain at least 3 paragraphs. Paragraphs are separated with the markdown divider: ***. Highlight at least 2 sections in your answer with markdown, i.e. *highlighted section*. Finish your response with this exact phrase [ender]. No other words should follow this phrase. [ender] is "Is there anything else I can help with?"
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