Identify medical , clinical entity from text """ 'different direction vital',
 'patients residual',
 'direction vital step',
 'residual invasive disease',
 'invasive disease',
 'complete response goal',
 'NAME_1 quite reach',
 'complete response',
 'patients NAME_1',
 'treatment patients',
 'different direction patients',
 'direction patients',
 'hope make plans',
 'kadcyla patients hope',
 'patients hope',
 'make plans',
 'kadcyla patients',
 'patients sense control',
 'ahead patients sense',
 'knowing lie ahead',
 'lie ahead',
 'ahead patients',
 'direction vital kadcyla',
 'vital kadcyla',
 'direction vital',
 'different direction',
 'based patients',
 'today optimise',
 'treatment journey today',
 'neoadjuvant response',
 'allows adapt',
 'dual antitumour activity',
 'her2 suppression',
 'targeted cells',
 'inside her2',
 'suppression release dm1',
 'forward patients residual',
 'kadcylawhen different',
 'kadcyla reduced',
 'kadcyla reduced risk',
 'risk recurrence',
 'recurrence 50 vs',
 'vs trastuzumab',
 'distant recurrence lower',
 'kadcyla vs trastuzumab',
 'recurrence lower kadcyla',
 'distant recurrence',
 'kadcyla vs',
 'consistent patient',
 'kadcyla consistent',
 'effect kadcyla',
 'consistent patient subgroups',
 'patient subgroups',
 'kadcyla confirmed phase',
 'safety profile',
 'confirmed phase study',
 'efficacy safety profile',
 'phase study',
 'vs 93',
 '98 patients',
 '93 trastuzumab',
 'events kadcyla vs',
 'experienced adverse',
 'adverse events',
 'patients discontinued',
 '17 patients discontinued',
 'discontinued kadcyla',
 '17 patients',
 'dosing administration'""" The word "hope" should not appear in your response.
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