You are a Systematic review assistant helping to screen abstracts for my study. Given the abstract, objectives and selection criteria should the study be included or excluded?
Abstract: Background The risk of cardiovascular disease is increased in the HIV population, potentially due to the additional burdens of infection, inflammation and antiretroviral treatment (ART). The effects of dietary intervention on cardiovascular risk (CVR) in HIV have not been well defined. We aim to examine the effect of two dietary interventions on CVR in HIV dyslipidaemia. Methods Sixty adults with stable HIV infection on ART and LDL\u2010cholesterol >3 mmol/l were recruited from three UK HIV centres. Participants were randomised (1 1) to receive dietary advice to reduce saturated fat intake to <10% of energy intake (Diet1), or to adopt the Mediterranean Portfolio Diet (Diet2) with additional cholesterol\u2010lowering foods (nuts, stanols, soya, oats, beans) for 12 months. Measurements of food intake, body composition, arterial stiffness, inflammation, CVR and fasting blood lipids were conducted at baseline, month 6 and 12. Between\u2010group changes of CV risk factors were assessed using ANCOVA, with adjustments for baseline values of the dependent variables. Analysis was by intention to treat. Ethical approval was granted (13/WM/0225). Results Baseline characteristics of the groups were comparable for age (mean 42\u20107 years), gender (50% female), smoking status (65% nonsmokers) ethnicity (50% black African, 40% white European) and lipid profile (mean LDL 3.9 0.6 mmol/l). Adherence to Portfolio components of Diet2 varied from 11 to 100% (mean 5921%). At 6 months, Diet2 participants (n=29) showed a greater increase in Mediterranean Diet Score (3.3 points, 95% CI 2.0 to 4.7, p<0.001), reduction in LDL\u2010cholesterol (0.4 mmol/l, 95% CI 0.7 to 0.1, p=0.01), cholesterol to HDL ratio (0.3 95% CI 0.6 to 0.1, p=0.01), and systolic blood pressure (7.2 mm Hg, 95% CI 1.6 to 12.8, p<0.001) than those in Diet1 (n=31). Arterial stiffness, body mass index, waist circumference, levels of physical activity and high sensitivity C\u2010reactive protein were not significantly different between groups. No adverse effects were observed in plasma levels of vitamin A, gut function, health related quality of life, or health and wellbeing. Conclusion Dietetic advice to follow a Mediterranean diet containing plant stanols, nuts, oats, beans and soya protein produced greater improvement in diet quality, CVR, and a 10% greater reduction in LDL\u2010cholest Limit your response to 250 words.
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